The role of autophagy in Parkinson's disease☆
نویسندگان
چکیده
Although Parkinson's disease is the most common neurodegenerative movement disorder, the mechanisms of pathogenesis remain poorly understood. Recent findings have shown that deregulation of the autophagy-lysosome pathway is involved in the pathogenesis of Parkinson's disease. This review summarizes the most recent findings and discusses the unique role of the autophagy-lysosome pathway in Parkinson's disease to highlight the possibility of Parkinson's disease treatment strategies that incorporate autophagy-lysosome pathway modulation.
منابع مشابه
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عنوان ژورنال:
دوره 7 شماره
صفحات -
تاریخ انتشار 2012